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Joseph Iskendiarso Sigit, Dr. rer. nat.

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  • Joseph Iskendiarso Sigit, Dr. rer. nat.


KK Farmakologi-Farmasi Klinik
Associate Professor

Email : jsigit at fa.itb.ac.id
Telepon : +62 22 250-4852

Bidang Keahlian

  1. Farmakologi Klinik Sistem Cardiovaskular dan Ginjal

Publikasi di Jurnal

  1. Hidayat, Y.A., Padmasawitri, T.I.A., Sigit, J.I., “Markov modeling for microvascular renal complication of niddm and hypertension to evaluate the use of angiotensin converting enzyme inhibitor (ACEI) and angiotensin receptor blocker (ARB)”,
    (2013), Lecture Notes in Engineering and Computer Science, 1 LNECS, pp. 59-64.
  2. Sukandar, E.Y., Sudjana, P., Sigit, J.I., Leliqia, N.P.E., Lestari, F., “Safety of garlic (allium sativum) and turmeric (curcuma domestica) extract in comparison with simvastatin on improving lipid profile in dyslipidemia patients”, (2013),  Journal of Medical Sciences (Faisalabad), 13 (1), pp. 10-18.
  3. Sukandar, E.Y., Sigit, J.I., Adiwibowo, L.F., “Study of kidney repair mechanisms of corn silk (Zea mays L. Hair)-binahong (Anredera cordifolia (Ten.) Steenis) leaves combination in rat model of kidney failure”, (2013), International Journal of Pharmacology, 9 (1), pp. 12-23.
  4. Sukandar, E.Y., Permana, H., Adnyana, I.K., Sigit, J.I., Ilyas, R.A., Hasimun, P., Mardiyah, D., “Clinical study of turmeric (Curcuma longa L.) and Garlic (Allium sativumL.) extracts as antihyperglycemic and antihyperlipidemic agent in type-2  diabetes-dyslipidemia patients”, (2010) International Journal of Pharmacology, 6 (4), pp. 438-445.
  5. Samsul Bahri, Joseph I. Sigit, Yusanti Ditia P., “Kadar Asam Laktat Hasil Metabolisme Anaerob pada Atlet”, Jurnal Iptek Olahraga Vol.11, Nomor 1, Januari 2009, Hal 59-74.
  6. Amalia, L., E.Y. Sukandar, RMA Roesli, JI Sigit, “The Effect of Ethanol Extract of Kucai (Allium schoenoprasum L.,) Bulbsa on Serum Nitric Oxide Level in Male Wistar Rats”, Int. J. Farmacol., 4(6), 2008
  7. Elin Yulinah, Joseph I. Sigit, Nurul Fitriyani., “Efek antiagregasi platelet ekatrak air bulbus bawang putih (Allium sativum L.), ekstrak etanol rimpang kunyit (Curcuma domestica Val.) dan kombinasinya pada mencit jantan galur Swiss Wecster”, Majalah Farmasi Indonesia, 19(1), 2008
  8. I Ketut Adnyana, Joseph I. Sigit, Eveline C. Samuels, Tennia P. Srani, “Aktivitas Antidiabetes dan Profil Keamanan Ekstrak Daging Biji Oyong (Luffa acutangula L. Roxb)”, Jurnal Acta Pharmaceutica Indonesia, Vol. XXXII, No. 2, Juni 2007
  9. Sigit, JI, ” Homocysteine a New Risk Factor for Cardiovascular Deasease” , Acta Pharmaceutica, 2004; XXIX:3
  10. Suwendar, Joseph I. Sigit, Pipih Sopiah, “Efek Stimulasi Sistem Saraf Pusat Infusa Rimpang Jahe (Zingiber officinale Rosc.) pada Mencit ddy”, Acta Pharmaceutica Indonesia, XXIX (2), 2004
  11. I Ketut Adnyana, Elin Yulinah, Andreanus A. Soemardji, Endang Kumolosasi, Maria Immaculata Iwo, Joseph I. Sigit, “Uji Aktivitas Antidiabetes Ekstrak Etanol Buah Mengkudu (Morinda citrifolia L.)”, Acta Pharmaceutica Indonesia, XXIX (2), 2004
  12. Sukandar, E.Y., Sigit, J.I., Adiwibowo, L.F., 2013, “Study of kidney repair mechanisms of corn silk (Zea mays L. Hair)-binahong (Anredera cordifolia (Ten.) Steenis) leaves combination in rat model of kidney failure”, International Journal of Pharmacology, 9 (1), pp. 12-23.
  13. Sukandar, E.Y., Sudjana, P., Sigit, J.I., Leliqia, N.P.E., Lestari, F., 2013, “Safety of garlic (allium sativum) and turmeric (curcuma domestica) extract in comparison with simvastatin on improving lipid profile in dyslipidemia patients”, Journal of Medical Sciences (Faisalabad), 13 (1), pp. 10-18.
  14. Sukandar, E.Y., Permana, H., Adnyana, I.K., Sigit, J.I., Ilyas, R.A., Hasimun, P., Mardiyah, D., 2010, “Clinical study of turmeric (Curcuma longa L.) and Garlic (Allium sativum L.) extracts as antihyperglycemic and antihyperlipidemic agent in type-2 diabetes-dyslipidemia patients”, International Journal of Pharmacology, 6 (4), pp. 438-445.

Publikasi di Konferensi

  1. Sigit JI, Padmasawitri TIA, Comparative Study of Anti Hypertension Drugs in the Perspective of Efficacy and Cost, a Case Study in Two hospital in Indonesia, The 10th Asian Conference on Clinical Pharmacy, July 9-12, 2010 Singapore.
  2. Evi Sovia, Elin Yulinah, Joseph I. Sigit and Lucy Dewi N. Sasongko, “Effects of Curcumin on Proliferation and Differentiation Human Primary Subcutaneous Preadipocytes”, Bandung International Conference on Medicinal Chemistry 6-8 August 2009
  3. Joseph I. Sigit, Dewi L. Ayu Ningtyas and Liza N. Zulkarnain, “The Effects of Artocarpus altilis Ethanol Extract and Maydis stigma Aqueous Extract Compare to Combination of Both Extracts to Renal Failure Rat Model”, Bandung International Conference on Medicinal Chemistry 6-8 August 2009
  4. Lia Amalia, Joseph I. Sigit and Devina Saputra, “Antihypertensive Effects of Cucumis sativus L. Extract in Male Wistar Rats Determined from Various Mechanisms”, Bandung International Conference on Medicinal Chemistry 6-8 August 2009
  5. Evi Sovia, Elin Yulinah Sukandar, Lucy Dewi Sasongko, Joseph I. Sigit, “Effect of Curcumin on Proliferation and Differentiation Human Primary Subcutaneus Preadipocytes”, The International Conference on Pharmacy and Advanced Pharmaceutical Sciences, Yogyakarta, October 5-6, 2009
  6. Amalia L. , Yulinah E., Roesli R.M.A., Sigit J.I., “THE EFFECT OF ETHANOL EXTRACT OF KUCAI
    (ALLIUM SCHOENOPRASUM L.) BULBS ON HEART RATE FREQUENCY AND AMPLITUDE IN HYPERTENSIVE-INDUCED MALE WISTAR RATS”, INTERNATIONAL HERBAL CONFERENCE 2009, FEBRUARY 26-28 2009, BANGALORE-INDIA
  7. Dinda Ayu Deliana, Lia Amalia, Joseph Sigit, “The Hipotensive Effect of Water Extract And Ethanol-Water Extract of Eleutherine Americana (Aubl.) Merr. In Male Wistar Rats Through Various Mechanism”, International Conference on Mathematics and Natural Science, ITB, 28-23 October 2008
  8. Joseph I Sigit, Elin Yulinah S., Dewi Mardiyah , Hikmat permana, Rikrik A. IIyas., “A Randomized Controlled Trial Extracts Of Turmeric (Curcuma Longa, L.) And Garlic (Allium Sativum, L.) As Antidiabetic In Type-2 Diabetes-Dislipidemic Subjects”, The 8th Asian Conference on Clinical Pharmacy, Surabaya, Indonesia, July 1-4, 2008
  9. Joseph Sigit, Armiin Stefani., “Antihypercholesterolemic Effect of Water Extract and Ethanol-Water Extract from Bulbs of Eleutherine americana (Aubl.) Merr. in Male Wistar Rats and Acute Toxicity Tests in Swiss Webster Mice”, International Conference on Mathematics and Natural Science, ITB, 28-23 October 2008
  10. Sri Rahayu, Utamy, Suwendar, Joseph I. Sigit, “Effect of Bitter Gourd (Momordica charantia L.) Water Extract on Uric Acid Serum Level of Hyperuri-cemic Cock Induced by High Purine Diet”, Proceeding Proceeding International Conference on Mathematics and Natural Science, 2006
  11. Sigit, JI., Manik Djatiningsih, I Ketut Adnyana,”Effect of Corn Silk (Maydis Stigma) Extract on Gentamicin-Piroxicam Induced Renal Failure Rat”, Proceeding International Conference on Mathematics and Natural Science, 2006
  12. Sigit, JI., Lia Meiliani, Heni Rachmawati,”The Method Development of Piroxicam- Gentamicin Induced Renal Failure Rat Model”, Proceeding International Conference on Mathematics and Natural Science, 2006
  13. Sigit, J.I., Elin Yulinah S., Fadhlina C., “The Development of hypercholesterolemic-diabetic Animal Model and The Effect of Drug on Lipoprotein and Glucose Profile”, Seminar MIPA V, 2004, ITB
  14. Sigit, JI, I Ketut Adnyana, Murti Widyaningsih, Dewi Fitriani, Elin Yulinah S.,”.DL- Homocysteine Hyperlipidemia Model and Screening Anhyperlipidemic Activity from Several Indonesian Traditional Medicinal Plants”, presented at The 6th Presentation of foundation Assited Research Findings Oveseas (Asahi Glass Foundation), ITB, 2004

Bantuan Penelitian

  1. Samsul Bahri, Joseph I. Sigit, Tommy Apriantono, Study of Supplement Administration on Lactic Acid Athlets, (2007). Research Grant ITB
  2. Joseph I. Sigit, I Ketut Adnyana, Neng Fisheri, Study of Eleutherine americana Bulb on Risk of Cardiovascular Disease, (2007), Research Grant of PHK A3
  3. Lia Amalia, Elin Yulinah S., J.I. Sigit, Uji aktivitas NO ekstrak kucai (Allium shoenoprasum), (2006), Research Grant ITB.
  4. Joseph I. Sigit, I Ketut Adnyana, Heni Rachmawati, Effect of Maydis stigma for the Treatment of Renal Failure, (2006), Research Grant ITB.
  5. Joseph I. Sigit, Elin YS, Widayat, Clinical Study of Kucai (Allium shoenoprasum) as Anti hypertension, (2005), Research Grant Badan POM RI.
  6. Elin YS., Joseph I. Sigit, Lia Amalia, Irda Fidriany, Antihypertension Effect of Kucai (Allium shoenoprasum), Riset Unggulan Terpadu, (2005), Ristek-RI.
  7. Asep Gana S., Elin Yulinah S., Joseph I. Sigit, I Ketut Adnyana, Hikmat, Clinical Study of Salam Leaf as Antidiabetes, (2004), Research Grant Badan POM RI

Pengalaman terkait dalam penelitian dan pendidikan

  1. Uji aktivitas anti anemia sediaan bahan alam (2005)
  2. Uji Klinik kucai sebagai anti hipertensi (2005)
  3. Uji Toksisitas akut likogen produk PT. Kalbe Farma (2005)
  4. Uji toksisitas subkronis ekstrak kucai Badan POM (2005)
  5. Uji aktivitas toksisitas subkronis kombinasi ekstrak jahe merah dan mengkudu Badan POM (2005)
  6. Uji Klinik Antidiabetes daun salam (2004)
  7. Uji Toksisitas akut daun salam (2004)
  8. Uji Toksisitas subkronis daun salam (2004)
  9. Uji Toksisitas Akut Ekstrak Loenorus (2003)
  10. Uji Toksisitas Akut Tablet Produk PJ. Bunga Teratai (2003)
  11. Uji Toksisitas Subkronik kombinasi ekstrak Loenorus, jahe dan pasak bumi (2003)
  12. Uji aktivitas afrodisiaka kombinasi ekstrak Loenorus, jahe dan pasak bumi (2003)
  13. Uji Toksisitas Berulang Vaksin dengan wadah silicon dan tanpa silicon produk PT Biofarma (2003)
  14. Uji Toksisitas Akut Ekstrak Daun salam (2003)
  15. Uji Toksisitas Subkronik Ekstrak Daun Salam (2003)
  16. Uji Aktivitas Antidiabetes Ekstrak Daun Salam (2003)
  17. Skin and Eye Irritation Test of Nature Shampoo Produced by PT Gondowangi Sariaji (2003)
  18. Skin and Eye Irritation Test of Nature Super Hair Grow Lotion Produced by PT Gondowangi Sariaji (2003)
  19. Skin and Eye Irritation Test of Nature Antidandruff Shampoo Produced by PT Gondowangi Sariaji (2003)
  20. Skin and Eye Irritation Test of Nature Hair Strengthener Produced by PT Gondowangi Sariaji (2003)
  21. Skin and Eye Irritation Test of Nature Hair Grow Cream Produced by PT Gondowangi Sariaji (2003)
  22. DL-Homocysteine Hyperlipidemia Model and Screening (2003)
  23. Antihyperlipidemic Activity from Several Indonesian Traditional Medicinal Plants (2003)
  24. Uji Toksisitas Akut Produk PT Martina Berto (2003)
  25. Efek antihiperlipidemia ekstrak bulbus bawang putih (Allium sativum) dan rimpang kunyit (Curcuma domestica) pada model hewan hiperlipidemia-diabetes serta pembuatan sediaan fitofarmakanya (2003)
  26. Uji Toksisitas Subkronis Serbuk B Produk PT. Sido Muncul (2002)
  27. Uji Toksisitas Subkronis Kapsul B Produk PT. Sido Muncul (2002)
  28. Uji Toksisitas Berulang Vaksin HIB Produk PT. Biofarma (2002)
  29. Uji Toksisitas Akut Vaksin HIB Produk PT. Biofarma (2002)
  30. Uji Aktivitas Afrodisiak Ekstrak Herba Leonorus sp. (2002)
  31. Uji Toksisitas Akut Jamu Bunga Teratai (2002)
  32. Assesment of Acute Oral Toxicity In ddY Mice of Paper (5) (2002)
  33. Uji Toksisitas Pemberian Berulang Vaksin Combo Biofarma (2002)
  34. Uji Toksisitas Akut Ekstrak Buah Mengkudu (2001)
  35. Uji Antimikroba Ekstrak Buah Mengkudu (2001)
  36. Uji Aktivitas Antidiabetes Ekstrak Buah Mengkudu (2001)
  37. Uji Toksisitas Subkronis Sediaan Prohepa, PT. Indofarma (2001)

Keanggotaan Organisasi Ilmiah

  1. Ikatan Sarjana Farmasi Indonesia (ISFI)
  2. Ikatan Ahli Farmakologi Indonesia (IKAFI)
  3. Ikatan Alumni DAAD

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