Dr. apt. Yuda Prasetya Nugraha, S.Farm., M.Si.



KK Farmasetika



Email: yudapn at itb.ac.id


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  • 2019: Pharmacist (Profesi Apoteker), School of Pharmacy, Bandung Institute of Technology
  • 2018: Doctor of Science, Department of Chemistry and Materials Science, Tokyo Institute of Technology, Japan
  • 2013: Master of Science, School of Pharmacy, Bandung Institute of Technology
  • 2012: Bachelor of Pharmacy, School of Pharmacy, Bandung Institute of Technology

Research Field

  • Pharmaceutical Solid Forms (Crystal Forms Screening, Structure Analysis, and Characterization)
  • Crystal Structure and Physicochemical Properties Relationship of Active Pharmaceutical Ingredients
  • Physical Pharmacy
  • Solid Dosage Form Development


  1. Kusuma, A. P.; Soewandhi, S. N.; Mauludin, R.; Suendo, V.; Kurniawan, F.; Pamungkas, G.; Nugraha, Y. P. Energetics of Carboxylic Acid–Pyridine Heterosynthon Revisited: A Computational Study of Intermolecular Hydrogen Bond Domination on Phenylacetic Acid–Nicotinamide Cocrystals. Open Chemistry 2022, 20 (1), 949–957. https://doi.org/10.1515/chem-2022-0207.
  2. Nugraha, Y. P.; Sugiyama, H.; Uekusa, H. Ciprofloxacin Salt and Salt Co-Crystal with Dihydroxybenzoic Acids. Acta Crystallographica Section E Crystallographic Communications 2022, 78 (3). https://doi.org/10.1107/S2056989022001177.
  3. Sriyanti, I.; Almafie, M. R.; Nugraha, Y. P.; Idjan, M. K. N. A.; Jauhari, J. The Morphology of Polyvinylpyrrolidone Nanofibers Containing Anredera Cordifolia Leaves. Jurnal Ilmiah Pendidikan Fisika Al-Biruni 2021, 10 (2), 13–23. https://doi.org/10.24042/jipfalbiruni.v10i2.8820.
  4. Indra, I.; Soewandhi, S. N.; Wikarsa, S.; Nugraha, Y. P. Designing and Characterization of Ramipril Spherical Agglomerates. International Journal of Pharmaceutical Research 2020, 12 (02), 3177–3183. https://doi.org/10.31838/ijpr/2020.12.02.426.
  5. Ainurofiq, A.; Setianto, A.; Nugraha, Y. P.; Suendo, V.; Uekusa, H.; Soewandhi, S. X-Ray Diffraction and Vibrational Spectroscopic Studies of the Intermolecular Interactions on the Grinding and Compaction Behaviours of Lopinavir and Ritonavir Crystals. Acta Poloniae Pharmaceutica – Drug Research 2020, 77 (2), 259–269. https://doi.org/10.32383/appdr/116562.
  6. Nurhayati; Suendo, V.; Alni, A.; Nugroho, A. A.; Majima, Y.; Lee, S.; Nugraha, Y. P.; Uekusa, H. Revealing the Real Size of a Porphyrin Molecule with Quantum Confinement Probing via Temperature-Dependent Photoluminescence Spectroscopy. The Journal of Physical Chemistry A 2020, 124 (13), 2672–2682. https://doi.org/10.1021/acs.jpca.0c00665.
  7. Nugrahani, I.; Utami, D.; Nugraha, Y. P.; Uekusa, H.; Hasianna, R.; Darusman, A. A. Cocrystal Construction between the Ethyl Ester with Parent Drug of Diclofenac: Structural, Stability, and Anti-Inflammatory Study. Heliyon 2019, 5 (12), e02946. https://doi.org/10.1016/j.heliyon.2019.e02946.
  8. Putra, O. D.; Pettersen, A.; Nilsson Lill, S. O.; Umeda, D.; Yonemochi, E.; Nugraha, Y. P.; Uekusa, H. Capturing a New Hydrate Polymorph of Amodiaquine Dihydrochloride Dihydrate via Heterogeneous Crystallisation. CrystEngComm 2019, 21 (13), 2053–2057. https://doi.org/10.1039/C8CE01720D.
  9. Putra, O. D.; Umeda, D.; Nugraha, Y. P.; Nango, K.; Yonemochi, E.; Uekusa, H. Simultaneous Improvement of Epalrestat Photostability and Solubility via Cocrystallization: A Case Study. Crystal Growth & Design 2018, 18 (1), 373–379. https://doi.org/10.1021/acs.cgd.7b01371.
  10. Nugrahani, I.; Utami, D.; Ibrahim, S.; Nugraha, Y. P.; Uekusa, H. Zwitterionic Cocrystal of Diclofenac and L-Proline: Structure Determination, Solubility, Kinetics of Cocrystallization, and Stability Study. European Journal of Pharmaceutical Sciences 2018, 117, 168–176. https://doi.org/10.1016/j.ejps.2018.02.020.
  11. Nugraha, Y. P.; Uekusa, H. Suppressed Hydration in Metoclopramide Hydrochloride by Salt Cocrystallisation. CrystEngComm 2018, 20 (19), 2653–2662. https://doi.org/10.1039/C8CE00129D.
  12. Putra, O. D.; Umeda, D.; Nugraha, Y. P.; Furuishi, T.; Nagase, H.; Fukuzawa, K.; Uekusa, H.; Yonemochi, E. Solubility Improvement of Epalrestat by Layered Structure Formation via Cocrystallization. CrystEngComm 2017, 19 (19), 2614–2622. https://doi.org/10.1039/C7CE00284J.
  13. Ismed, F.; Farhan, A.; Bakhtiar, A.; Zaini, E.; Nugraha, Y. P.; Putra, O. D.; Uekusa, H. Crystal Structure of Olivetolic Acid: A Natural Product from Cetrelia Sanguinea (Schaer.). Acta Crystallographica Section E Crystallographic Communications 2016, 72 (11), 1587–1589. https://doi.org/10.1107/S2056989016016273.


  1. Nugraha, Y.; Utama, V.K.; Uekusa H.; Soewandhi, S.N. Poster Presentation: Salt Cocrystallization of Metoclopramide: The Role of Coformer in Tuning Physicochemical Properties. 11th Crystal Forms @Bologna (CF@BO), Online Convention, September 10–11, 2021.
  2. Nugraha, Y.; Sugiyama, H.; Soewandhi, S.N.; Uekusa, H. Poster Presentation: Phase Transformation of Metoclopramide Polymorphs. The 1st International Conference on Pharmacy and Pharmaceutical Sciences (ICPSP 2020), Virtual Conference by the School of Pharmacy ITB, October 7–8, 2020.
  3. Nugraha, Y.; Soewandhi, S.N.; Uekusa, H. Poster Presentation: Improving the Stability of Pharmaceutical Salt Hydrate by Cocrystallization. 16th Conference of the Asian Crystallographic Association (AsCA 2019), NUS, Singapore, December 17­­–20, 2019.
  4. Nugraha, Y.P.; Uekusa, H. Poster Presentation: Stability Improvement of Metoclopramide Hydrochloride by Cocrystallization. The 3rd Asian Conference on Pharmaceutical Sciences (AsiaPharm), Bali, Indonesia, July 2–4, 2018.
  5. Nugraha, Y.P.; Uekusa, H. Poster Presentation: Suppressing Hydrate Formation in Metoclopramide HCl by Cocrystallization’ The IX Bologna’s Convention on Crystal Forms, University of Bologna, Italy, June 4–6,
  6. Nugraha, Y.P.; Uekusa, H. Oral Presentation: Structure-Property Relationship of Pharmaceutical Pseudopolymorph. International Symposium on Pure & Applied Chemistry (ISPAC 2016), Kuching, Malaysia, August 16–18,
  7. Nugraha, Y.P.; Sekine, A.; Uekusa, H. Poster Presentation: Crystal Structural Insights into Dehydration of Metoclopramide HCl Monohydrate. The 136th Annual Meeting of the Pharmaceutical Society of Japan, Yokohama, Japan, March 26–29,
  8. Nugraha, Y.P.; Putra, O.; Uekusa, H. Poster Presentation: Crystal structures and desolvations of metoclopramide hydrochloride monohydrate and solvates. The International Chemical Congress of Pacific Basin Societies (Pacifichem 2015), Honolulu, Hawaii, USA, December 15–20, 2015.

Short Courses

  1. Rigaku School for Practical Crystallography (June 1–12, 2020)
  2. Short-term Research at Prof. Kenneth D. M. Harris’ Laboratory, Cardiff University (February 2016)
  3. The 7th AONSA Neutron School/3rd MLF School, J-PARC, Japan (December 1–5, 2015)



  1. Best Poster Award by Cambridge Crystallographic Data Center (CCDC) for the Year 2019 on Chemical Crystallography, AsCA 2019
  2. MEXT Scholarship for Research Student and Doctoral Program (2014-2018)
  3. Beasiswa Unggulan DIKTI for Master Program (2012-2013)