KK Farmasetika
Instructor
Email: yudapn at itb.ac.id
Education
- 2019: Pharmacist (Profesi Apoteker), School of Pharmacy, Bandung Institute of Technology
- 2018: Doctor of Science, Department of Chemistry and Materials Science, Tokyo Institute of Technology, Japan
- 2013: Master of Science, School of Pharmacy, Bandung Institute of Technology
- 2012: Bachelor of Pharmacy, School of Pharmacy, Bandung Institute of Technology
Research Field
- Pharmaceutical Solid Forms (Crystal Forms Screening, Structure Analysis, and Characterization)
- Crystal Structure and Physicochemical Properties Relationship of Active Pharmaceutical Ingredients
- Physical Pharmacy
- Solid Dosage Form Development
Publications
- Kusuma, A. P.; Soewandhi, S. N.; Mauludin, R.; Suendo, V.; Kurniawan, F.; Pamungkas, G.; Nugraha, Y. P. Energetics of Carboxylic Acid–Pyridine Heterosynthon Revisited: A Computational Study of Intermolecular Hydrogen Bond Domination on Phenylacetic Acid–Nicotinamide Cocrystals. Open Chemistry 2022, 20 (1), 949–957. https://doi.org/10.1515/chem-2022-0207.
- Nugraha, Y. P.; Sugiyama, H.; Uekusa, H. Ciprofloxacin Salt and Salt Co-Crystal with Dihydroxybenzoic Acids. Acta Crystallographica Section E Crystallographic Communications 2022, 78 (3). https://doi.org/10.1107/S2056989022001177.
- Sriyanti, I.; Almafie, M. R.; Nugraha, Y. P.; Idjan, M. K. N. A.; Jauhari, J. The Morphology of Polyvinylpyrrolidone Nanofibers Containing Anredera Cordifolia Leaves. Jurnal Ilmiah Pendidikan Fisika Al-Biruni 2021, 10 (2), 13–23. https://doi.org/10.24042/jipfalbiruni.v10i2.8820.
- Indra, I.; Soewandhi, S. N.; Wikarsa, S.; Nugraha, Y. P. Designing and Characterization of Ramipril Spherical Agglomerates. International Journal of Pharmaceutical Research 2020, 12 (02), 3177–3183. https://doi.org/10.31838/ijpr/2020.12.02.426.
- Ainurofiq, A.; Setianto, A.; Nugraha, Y. P.; Suendo, V.; Uekusa, H.; Soewandhi, S. X-Ray Diffraction and Vibrational Spectroscopic Studies of the Intermolecular Interactions on the Grinding and Compaction Behaviours of Lopinavir and Ritonavir Crystals. Acta Poloniae Pharmaceutica – Drug Research 2020, 77 (2), 259–269. https://doi.org/10.32383/appdr/116562.
- Nurhayati; Suendo, V.; Alni, A.; Nugroho, A. A.; Majima, Y.; Lee, S.; Nugraha, Y. P.; Uekusa, H. Revealing the Real Size of a Porphyrin Molecule with Quantum Confinement Probing via Temperature-Dependent Photoluminescence Spectroscopy. The Journal of Physical Chemistry A 2020, 124 (13), 2672–2682. https://doi.org/10.1021/acs.jpca.0c00665.
- Nugrahani, I.; Utami, D.; Nugraha, Y. P.; Uekusa, H.; Hasianna, R.; Darusman, A. A. Cocrystal Construction between the Ethyl Ester with Parent Drug of Diclofenac: Structural, Stability, and Anti-Inflammatory Study. Heliyon 2019, 5 (12), e02946. https://doi.org/10.1016/j.heliyon.2019.e02946.
- Putra, O. D.; Pettersen, A.; Nilsson Lill, S. O.; Umeda, D.; Yonemochi, E.; Nugraha, Y. P.; Uekusa, H. Capturing a New Hydrate Polymorph of Amodiaquine Dihydrochloride Dihydrate via Heterogeneous Crystallisation. CrystEngComm 2019, 21 (13), 2053–2057. https://doi.org/10.1039/C8CE01720D.
- Putra, O. D.; Umeda, D.; Nugraha, Y. P.; Nango, K.; Yonemochi, E.; Uekusa, H. Simultaneous Improvement of Epalrestat Photostability and Solubility via Cocrystallization: A Case Study. Crystal Growth & Design 2018, 18 (1), 373–379. https://doi.org/10.1021/acs.cgd.7b01371.
- Nugrahani, I.; Utami, D.; Ibrahim, S.; Nugraha, Y. P.; Uekusa, H. Zwitterionic Cocrystal of Diclofenac and L-Proline: Structure Determination, Solubility, Kinetics of Cocrystallization, and Stability Study. European Journal of Pharmaceutical Sciences 2018, 117, 168–176. https://doi.org/10.1016/j.ejps.2018.02.020.
- Nugraha, Y. P.; Uekusa, H. Suppressed Hydration in Metoclopramide Hydrochloride by Salt Cocrystallisation. CrystEngComm 2018, 20 (19), 2653–2662. https://doi.org/10.1039/C8CE00129D.
- Putra, O. D.; Umeda, D.; Nugraha, Y. P.; Furuishi, T.; Nagase, H.; Fukuzawa, K.; Uekusa, H.; Yonemochi, E. Solubility Improvement of Epalrestat by Layered Structure Formation via Cocrystallization. CrystEngComm 2017, 19 (19), 2614–2622. https://doi.org/10.1039/C7CE00284J.
- Ismed, F.; Farhan, A.; Bakhtiar, A.; Zaini, E.; Nugraha, Y. P.; Putra, O. D.; Uekusa, H. Crystal Structure of Olivetolic Acid: A Natural Product from Cetrelia Sanguinea (Schaer.). Acta Crystallographica Section E Crystallographic Communications 2016, 72 (11), 1587–1589. https://doi.org/10.1107/S2056989016016273.
Conferences
- Nugraha, Y.; Utama, V.K.; Uekusa H.; Soewandhi, S.N. Poster Presentation: Salt Cocrystallization of Metoclopramide: The Role of Coformer in Tuning Physicochemical Properties. 11th Crystal Forms @Bologna (CF@BO), Online Convention, September 10–11, 2021.
- Nugraha, Y.; Sugiyama, H.; Soewandhi, S.N.; Uekusa, H. Poster Presentation: Phase Transformation of Metoclopramide Polymorphs. The 1st International Conference on Pharmacy and Pharmaceutical Sciences (ICPSP 2020), Virtual Conference by the School of Pharmacy ITB, October 7–8, 2020.
- Nugraha, Y.; Soewandhi, S.N.; Uekusa, H. Poster Presentation: Improving the Stability of Pharmaceutical Salt Hydrate by Cocrystallization. 16th Conference of the Asian Crystallographic Association (AsCA 2019), NUS, Singapore, December 17–20, 2019.
- Nugraha, Y.P.; Uekusa, H. Poster Presentation: Stability Improvement of Metoclopramide Hydrochloride by Cocrystallization. The 3rd Asian Conference on Pharmaceutical Sciences (AsiaPharm), Bali, Indonesia, July 2–4, 2018.
- Nugraha, Y.P.; Uekusa, H. Poster Presentation: Suppressing Hydrate Formation in Metoclopramide HCl by Cocrystallization’ The IX Bologna’s Convention on Crystal Forms, University of Bologna, Italy, June 4–6,
- Nugraha, Y.P.; Uekusa, H. Oral Presentation: Structure-Property Relationship of Pharmaceutical Pseudopolymorph. International Symposium on Pure & Applied Chemistry (ISPAC 2016), Kuching, Malaysia, August 16–18,
- Nugraha, Y.P.; Sekine, A.; Uekusa, H. Poster Presentation: Crystal Structural Insights into Dehydration of Metoclopramide HCl Monohydrate. The 136th Annual Meeting of the Pharmaceutical Society of Japan, Yokohama, Japan, March 26–29,
- Nugraha, Y.P.; Putra, O.; Uekusa, H. Poster Presentation: Crystal structures and desolvations of metoclopramide hydrochloride monohydrate and solvates. The International Chemical Congress of Pacific Basin Societies (Pacifichem 2015), Honolulu, Hawaii, USA, December 15–20, 2015.
Short Courses
- Rigaku School for Practical Crystallography (June 1–12, 2020)
- Short-term Research at Prof. Kenneth D. M. Harris’ Laboratory, Cardiff University (February 2016)
- The 7th AONSA Neutron School/3rd MLF School, J-PARC, Japan (December 1–5, 2015)
Awards
- Best Poster Award by Cambridge Crystallographic Data Center (CCDC) for the Year 2019 on Chemical Crystallography, AsCA 2019
- MEXT Scholarship for Research Student and Doctoral Program (2014-2018)
- Beasiswa Unggulan DIKTI for Master Program (2012-2013)